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Measure liver tests promptly in patients who report symptoms that may indicate liver injury.including fatigue.anorexia.right upper abdominal discomfort.dark urine or jaundice. In this clinical context.if the patient is found to have purchase duetact manufacturer liver tests (ALT greater than 3 times the upper limit of the reference range).DUETACT treatment should be interrupted and investigation done to establish the probable cause. DUETACT should not purchase duetact manufacturer restarted in these patients without another explanation for the liver test abnormalities.

If the patient is a child. Do not give Duetact (pioglitazone and glimepiride) to a child.

Read this Medication Guide carefully before you start taking DUETACT and each time you get a refill. There may be new information. This information purchase duetact manufacturer not take the place of talking with your doctor about your medical condition or your treatment. If you have any questions about DUETACT.ask your doctor or pharmacist.

For more information on this medication choose from the list of selections below.

Pioglitazone may be associated with an increase in the risk of urinary bladder tumors. There purchase duetact manufacturer insufficient data to determine whether pioglitazone is a tumor promoter for urinary bladder tumors.

Patients with type 2 diabetes may have fatty liver disease or cardiac disease with episodic congestive heart failure.both of which may cause liver test abnormalities.and they may also have other forms of liver disease.many of which can be treated or managed. Therefore.obtaining a liver test panel (serum alanine aminotransferase [ALT].aspartate aminotransferase [AST].alkaline phosphatase.and total bilirubin) and assessing the patient is recommended before initiating Duetact therapy. In patients with abnormal liver tests.Duetact should be initiated with caution.

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